2-(Methyloxy)benzenesulfonyl chloride
2-Methoxybenzenesulfonyl Chloride
CAS: 10130-87-7
Molecular Formula: C7H7ClO3S
2-(Methyloxy)benzenesulfonyl chloride - Names and Identifiers
2-(Methyloxy)benzenesulfonyl chloride - Physico-chemical Properties
| Molecular Formula | C7H7ClO3S |
| Molar Mass | 206.65 |
| Density | 1.376 |
| Melting Point | 50-54°C |
| Boling Point | 126-129 °C(Press: 0.3 Torr) |
| Flash Point | 138.3°C |
| Vapor Presure | 0.00152mmHg at 25°C |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Sensitive | Moisture Sensitive |
| Refractive Index | 1.535 |
2-(Methyloxy)benzenesulfonyl chloride - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R34 - Causes burns R43 - May cause sensitization by skin contact |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S36/37 - Wear suitable protective clothing and gloves. |
| UN IDs | 3261 |
| Hazard Class | IRRITANT |
| Packing Group | Ⅲ |
2-(Methyloxy)benzenesulfonyl chloride - Introduction
2-Methoxybenzenesulfonyl chloride is an organic compound with the chemical formula C8H9ClO3S. Its properties are as follows:
1. Appearance: 2-methoxybenzenesulfonyl chloride is a colorless to pink crystalline solid.
2. Solubility: It is insoluble in water, but soluble in organic solvents such as ether, chloroform and alcohols.
3. smell: it has a spicy smell.
2-methoxybenzenesulfonyl chloride is commonly used in organic synthesis and pharmaceutical fields, and its main uses include:
1. can be used as benzene sulfonic acid ester synthesis reagent.
2. It can be used as a deprotecting reagent and a chlorinating agent in the synthesis of drugs, especially amino acid derivatives and drug intermediates.
3. It can also be used as a synthetic reagent for dyes and pigments.
The preparation method of 2-methoxybenzenesulfonyl chloride is generally to react methoxybenzenesulfonic acid with thionyl chloride under appropriate reaction conditions to generate 2-methoxybenzenesulfonyl chloride.
When using 2-methoxybenzenesulfonyl chloride, you need to pay attention to the following safety information:
1. It is an organic synthetic reagent and should avoid direct contact with skin, eyes and mouth.
2. During operation, it should be carried out in a well-ventilated place to avoid inhaling its steam or dust.
3. Use personal protective equipment such as protective gloves, goggles and protective clothing.
4. For detailed safety information about the specific operation and handling of the compound, it is recommended to check the relevant safety data sheet.
1. Appearance: 2-methoxybenzenesulfonyl chloride is a colorless to pink crystalline solid.
2. Solubility: It is insoluble in water, but soluble in organic solvents such as ether, chloroform and alcohols.
3. smell: it has a spicy smell.
2-methoxybenzenesulfonyl chloride is commonly used in organic synthesis and pharmaceutical fields, and its main uses include:
1. can be used as benzene sulfonic acid ester synthesis reagent.
2. It can be used as a deprotecting reagent and a chlorinating agent in the synthesis of drugs, especially amino acid derivatives and drug intermediates.
3. It can also be used as a synthetic reagent for dyes and pigments.
The preparation method of 2-methoxybenzenesulfonyl chloride is generally to react methoxybenzenesulfonic acid with thionyl chloride under appropriate reaction conditions to generate 2-methoxybenzenesulfonyl chloride.
When using 2-methoxybenzenesulfonyl chloride, you need to pay attention to the following safety information:
1. It is an organic synthetic reagent and should avoid direct contact with skin, eyes and mouth.
2. During operation, it should be carried out in a well-ventilated place to avoid inhaling its steam or dust.
3. Use personal protective equipment such as protective gloves, goggles and protective clothing.
4. For detailed safety information about the specific operation and handling of the compound, it is recommended to check the relevant safety data sheet.
Last Update：2024-04-09 19:05:44
